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Phentermine

Phentermine the pill belongs to the category of centrally acting drugs known as amphetamines. It stimulates the sympathetic nervous system and produce a feeling of satiety. It is speculated that this action, along with as yet undetermined effects on the metabolism are responsible for the loss of appetite seen in this class of drugs. Phentermine can be a good choice for individuals, whose eating habits or behavior alone is responsible for excessive weight gain.
Researches show that the effectiveness of Phentermine diet pills have an average weight loss of 2-8 kg more than placebo for the same duration of treatment.

The weight loss produced by Phentermine diet pills is greatest during the first few weeks of therapy, then its beneficial effect wears off gradually. Therefore it is best for short term weight management and has to be taken with a restricted calorie diet to produce maximum benefit. At the end of the four week treatment period, the therapy needs to be reevaluated in every case, at the end of this time, a weight reduction of at least 2 kg should have been achieved. This is a predictor that the drug is going to work in a particular individual, if this minimal weight loss is not achieved, a different class of drug may need to be used.

Caution is advised when Phentermine diet pills are taken together with other drugs that act on the brain and the heart. If co-administered with other weight loss drugs such as Fenfluramine, they increase the resistance to blood flow in the lung and even cause defects in the heart valves. It also should never be given along with MAO inhibitors (a class of antidepressant drugs) for fear of acute elevations in blood pressure. Effects on pregnant and breastfeeding mothers has not been studied enough, so it is recommended that the drug NOT be used in these groups.

It has also not been tested sufficiently in younger age-groups and should not be prescribed to children less than 16 years old. It is also not recommended if pre-existing anxiety states, severe hypertension, advanced coronary heart disease, dysfunction of the heart valves, drug abuse, glaucoma or hypersensitivity to this drug class are known or suspected; alcohol consumption may also produce an adverse drug reaction.

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